EXPANSION OF CD62L-EXPRESSING MYELOID-DERIVED SUPPRESSOR CELLS IN INFLAMMATION- RELATED TUMOR PROGRESSION

N. Abdolla; Y.V. Perfilyeva; Y.O. Ostapchuk; R. Tleulieva; V.C. Krasnoshtanov; N.N. Belyaev; N.N. Belyaev; M.A. Aitkhozhin

doi:10.29256/v.02.02.2018.escbm06

N. Abdolla Al-Farabi Kazakh National University, Kazakhstan
Y.V. Perfilyeva Institute of Molecular Biology and Biochemistry, Laboratory of Molecular Immunology and Immunobiotechnology, Kazakhstan
Y.O. Ostapchuk Institute of Molecular Biology and Biochemistry, Laboratory of Molecular Immunology and Immunobiotechnology, Kazakhstan
R. Tleulieva Institute of Molecular Biology and Biochemistry, Laboratory of Molecular Immunology and Immunobiotechnology, Kazakhstan
V.C. Krasnoshtanov Kazakh Research Institute of Oncology & Radiology, Kazakhstan
N.N. Belyaev Saint-Petersburg Pasteur Institute, Saint-Petersburg, Russia
N.N. Belyaev Institute of Molecular Biology and Biochemistry, Laboratory of Molecular Immunology and Immunobiotechnology, Kazakhstan
M.A. Aitkhozhin Institute of Molecular Biology and Biochemistry, Laboratory of Molecular Immunology and Immunobiotechnology, Kazakhstan

DOI: https://doi.org/10.29256/v.02.02.2018.escbm06

Keywords: chronic inflammation, CD62L, myeloid-derived suppressor cells, adjuvant arthritis

Abstract

EXPANSION OF CD62L-EXPRESSING MYELOID-DERIVED SUPPRESSOR CELLS IN INFLAMMATION- RELATED TUMOR PROGRESSION

References

1. Wang D., DuBois R.N. Immunosuppression associated with chronic inflammation in the tumor microenvironment // Carcinogenesis. – 2015. - N10(36).- P.1085–93

2. Bronte V., Brandau S., Chen S.H., Colombo M.P., Frey A.B., Greten T.F., et al. Recommendations for myeloid-derived suppressor cell nomenclature and characterization standards//Nat. Commun.- 2016.- Vol.7:12150. doi:10.1038/ ncomms12150.

3. Marigo I, Bosio E, Solito S, Mesa C, Fernandez A, et al. Tumor-induced tolerance and immune suppression depend on the C/EBPbeta transcription factor// Immunity -2010.-N 32.-P. 790–802.