C-REACTIV PROTEIN AND NEUTROPHIL - LYMPHOCYTE RATION AS POTENTIAL BIOMARKERS OF INFLAMATION IN PATIENTS WITH NON-VALVULAR ATRIAL FIBRILLATION


  • O. Bernaz State University of Medicine and Pharmacy “Nicolae Testemiţanu”, Republic of Moldova
  • A. Vinevschi State University of Medicine and Pharmacy “Nicolae Testemiţanu”, Republic of Moldova
Keywords: Non-valvular atrial fibrillation, C-reactive protein (CRP), neutrophil-lymphocyte ratio (RNL).

Abstract

C-REACTIV PROTEIN AND NEUTROPHIL - LYMPHOCYTE RATION AS POTENTIAL BIOMARKERS OF INFLAMATION IN PATIENTS WITH NON-VALVULAR ATRIAL FIBRILLATION

References

1. Hijazi, Z., Oldgren, J., Siegbahn, A., Granger, C. B., & Wallentin, L. (2013). Biomarkers in atrial fibrillation: A clinical review. European Heart Journal, 34(20), 1475–1480. https://doi.org/10.1093/eurheartj/eht024.

2. Lip GY, Patel JV, Hughes E, et al. High-sensitivity C-reactive protein and soluble CD40 ligand as indices of inflammation and platelet activation in 880 patients with non-valvular atrial fibrillation: relationship to stroke risk factors, stroke risk stratification schema, and prognosis. Stroke. 2007;38:1229–1237.

3. Chung MK, Martin DO, Sprecher D, et al. C-reactive protein elevation in patients with atrial arrhythmias: inflammatory mechanisms and persistence of atrial fibrillation. Circulation. 2001;104:2886–2891.

4. Galea, R., Cardillo, M. T., Caroli, A., Marini, M. G., Sonnino, C., Narducci, M. L., & Biasucci, L. M. (2014). Inflammation and C-reactive protein in atrial fibrillation: Cause or effect? Texas Heart Institute Journal, 41(5), 461–468. https://doi. org/10.14503/THIJ-13-3466.

5. Conway DS, Buggins P, Hughes E, Lip GY. Relationship of interleukin-6 and C-reactive protein to the prothrombotic state in chronic atrial fibrillation. J Am Coll Cardiol 2004;43 (11):2075-82.

6. Tousoulis D, Zisimos K, Antoniades C, Stefanadi E, Siasos G, Tsioufis C, et al. Oxidative stress and inflammatory process in patients with atrial fibrillation: the role of left atrium distension. Int J Cardiol 2009;136(3):258-62.

7. Lip GY, Patel JV, Hughes E, Hart RG. High-sensitivity C-reactive protein and soluble CD40 ligand as indices of inflammation and platelet activation in 880 patients with non-valvular atrial fibrillation: relationship to stroke risk factors, stroke risk stratification schema, and prognosis. Stroke 2007;38(4):1229-37.

8. Akpek M, Kaya MG, Lam YY, et al. Relation of neutrophil/lymphocyte ratio to coronary flow to in-hospital major adverse cardiac events in patients with ST-elevated myocardial infarction undergoing primary coronary intervention. Am J Cardiol. 2012;110:621–627.

9. Cosansu, K., Vatan, M. B., Gunduz, H., & Akdemir, R. (2018). Use of neutrophil-lymphocyte ratio for risk stratification and relationship with time in therapeutic range in patients with non-valvular atrial fibrillation: A pilot study. Clinical Cardiology, 41(3), 339–342. https://doi.org/10.1002/clc.22869.

10. Yalcin M, Aparci M, Uz O, et al. Neutrophil-lymphocyte ratio may predict left atrial thrombus in K., Vatan, M. B., Gunduz, H., & Akdemir, R. (2018). Use of neutrophil-lymphocyte ratio for risk stratification and relationship with time in therapeutic range in patients with non-valvular atrial fibrillation: A pilot study. Clinical Cardiology, 41(3), 339–342. Htt patients with non-valvular atrial fibrillation. Clin Appl Thromb Hemost. 2015;21:166–171.

11. Dernellis J, Panaretou M. Effects of C-reactive protein and the third and fourth components of complement (C3 and C4) on incidence of atrial fibrillation. Am J Cardiol 2006;97(2):245- 8.
Published
2019-11-07
How to Cite
Bernaz, O., & Vinevschi, A. (2019). C-REACTIV PROTEIN AND NEUTROPHIL - LYMPHOCYTE RATION AS POTENTIAL BIOMARKERS OF INFLAMATION IN PATIENTS WITH NON-VALVULAR ATRIAL FIBRILLATION. Biological Markers in Fundamental and Clinical Medicine (scientific Journal), 3(1), 21-22. https://doi.org/10.29256/v.03.01.2019.escbm12
Section
Selected abstracts